Trajectory Enrichment Analysis
Assess whether a user-provided gene set is significantly enriched in specific aging trajectory patterns across species and tissues. Statistical significance is evaluated using the hypergeometric distribution with Benjamini-Hochberg multiple testing correction.
Notation:
k/n — k (observed): genes in this pattern / n (matched): user genes mapped to tissue trajectory
M/N — M (background pattern): genes in this pattern in the background / N (total background): all trajectory-annotated genes in this tissue
Hypergeometric test P(X ≥ k) | BH-adjusted FDR | * < 0.05, ** < 0.01, *** < 0.001
Enter Gene List
Computing enrichment statistics across species...